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Yes, Acupuncture Works - In the World Press: (Go to Original Research Paper)
The Nation - Jul 22, 2015
'This research, the culmination of a number of studies, demonstrates how acupuncture might work in the human body to reduce stress and pain, and potentially, depression.' Her work will provide a sense of vindication for those who have spent hundreds of ...
Chinatopix - Jul 22, 2015
Electro-acupuncture is a therapy that involves passing very minimal voltage of electric current between a pair of needles onto the pathway related to chronic pain, mood and stress, according to The Guardian. Acupuncture is done to unlock the energy ...
Bioscience Technology - Jul 22, 2015
In animal models, acupuncture appears to impact the same biologic pathways ramped up by pain and stress, analogous to what drugs do in humans. Georgetown University Medical Center (GUMC) researchers say their animal study, published online in ...
International Business Times - Jul 22, 2015
Acupuncture was found to be effective in the treatment of chronic anxiety and stress in rats, says a recent report published in the journal Endocrinology. The researchers at Georgetown University Medical Center in Washington, D.C., say acupuncture can ...
Acupuncture May Work Like Drugs To Relieve Stress | Popular Science
Popular Science - Jul 22, 2015
The thought of having needles inserted into your body may sound stressful. But to those who regularly receive acupuncture treatments, it's quite relaxing, though scientists haven't really been sure why. Now researchers from Georgetown University have ...
Independent Online - Jul 22, 2015
Study author Ladan Eshkevari said the research demonstrates how acupuncture may “reduce stress and pain, and potentially depression”. Dr Eshkevari, of Georgetown University in Washington, DC, gave acupuncture to rats that had regularly been exposed ...
HealthCentral.com - Jul 22, 2015
Acupuncture can do more than relieve stiff or painful muscles, according to a study at Georgetown University Medical Center. Researchers there found that it may also be effective in reducing stress, and potentially depression. The scientists divided ...
Genetic Engineering & Biotechnology News (blog) - Jul 22, 2015
Acupuncture appears to impact the same biologic pathways ramped up by pain and stress in animal models, analogous to what drugs do in humans, according to scientists at Georgetown University Medical Center (GUMC). The researchers say their study ...
Genetic Engineering & Biotechnology News - Jul 22, 2015
Acupuncture appears to impact the same biologic pathways ramped up by pain and stress in animal models, analogous to what drugs do in humans, according to scientists at Georgetown University Medical Center (GUMC). The researchers say their study ...
TV3.ie - Jul 22, 2015
However a new US study has found evidence that acupuncture really can reduce stress, pain and even depression. The research looked at the effect of acupuncture on rats that had been exposed to extreme cold on numerous occasions. This was intended to ...
Daily Mail - Jul 22, 2015
How acupuncture 'really can ease pain': Ancient Chinese art can have genuine benefits and could reduce stress and potentially depression, research suggests. New study claims acupuncture may 'reduce stress, pain and depression'; Ancient Chinese art ...
Medical News Today - Jul 22, 2015
"This is the first report linking the effects of electro-acupuncture at St36 to chronic stress-induced depressive and anxious behavior in animals" - acupuncture appeared to prevent stress-induced release of hormones, as well as reduce depression and ...
Western Daily Press - Jul 21, 2015
"This research, the culmination of a number of studies, demonstrates how acupuncture might work in the human body to reduce stress and pain, and potentially depression. We have now found a potential mechanism, and at this point in our research, we need ...
SBS - Jul 21, 2015
The study, reported in the journal Endocrinology, compared stressed rats given electroacupuncture, a "sham" therapy in which needles were not inserted in a meridian point, or no treatment. A fourth group of rats were not exposed to stress, and did not ...
The Daily Telegraph - Jul 21, 2015
The study, reported in the journal Endocrinology, compared stressed rats given electroacupuncture, a "sham" therapy in which needles were not inserted in a meridian point, or no treatment. A fourth group of rats were not exposed tostress, and did not ...
NEWS.com.au - Jul 21, 2015
"This research, the culmination of a number of studies, demonstrates how acupuncture might work in the human body to reduce stress and pain, and potentially depression. We have now found a potential mechanism, and at this point in our research, we need ...
The Australian (blog) - Jul 21, 2015
"This research, the culmination of a number of studies, demonstrates how acupuncture might work in the human body to reduce stress and pain, and potentially depression. We have now found a potential mechanism, and at this point in our research, we need ...
The Cairns Post - Jul 21, 2015
"This research, the culmination of a number of studies, demonstrates how acupuncture might work in the human body to reduce stress and pain, and potentially depression. We have now found a potential mechanism, and at this point in our research, we need ...
Herald Sun - Jul 21, 2015
The study, reported in the journal Endocrinology, compared stressed rats given electroacupuncture, a "sham" therapy in which needles were not inserted in a meridian point, or no treatment. A fourth group of rats were not exposed tostress, and did not ...
Courier Mail - Jul 21, 2015
The study, reported in the journal Endocrinology, compared stressed rats given electroacupuncture, a "sham" therapy in which needles were not inserted in a meridian point, or no treatment. A fourth group of rats were not exposed tostress, and did not ...
NT News - Jul 21, 2015
"This research, the culmination of a number of studies, demonstrates how acupuncture might work in the human body to reduce stress and pain, and potentially depression. We have now found a potential mechanism, and at this point in our research, we need ...
Pharmaceutical Processing - Jul 21, 2015
WASHINGTON -- In animal models, acupuncture appears to impact the same biologic pathways ramped up by pain and stress, analogous to what drugs do in humans. Georgetown University Medical Center (GUMC) researchers say their animal study, ...
Newswise (press release) - Jul 21, 2015
Newswise — WASHINGTON (July 21, 2015) — In animal models, acupuncture appears to impact the same biologic pathways ramped up by pain and stress, analogous to what drugs do in humans. Georgetown University Medical Center (GUMC) researchers ...
TIME - Jul 21, 2015
“There was nothing in the literature about acupuncture for PTSD and chronic stress,” she says, so she decided to study it. To find out if acupuncture was affecting chronic stress, Eshkevari and a team of researchers looked at what happened in a key ...
Medical Xpress - Jul 21, 2015
In animal models, acupuncture appears to impact the same biologic pathways ramped up by pain and stress, analogous to what drugs do in humans. Georgetown University Medical Center (GUMC) researchers say their animal study, published online in ...
The Guardian - Jul 21, 2015
“This research, the culmination of a number of studies, demonstrates how acupuncture might work in the human body to reduce stress and pain, and potentially depression. We have now found a potential mechanism, and at this point in our research, we need ...
Yahoo News UK - Jul 21, 2015
"This research, the culmination of a number of studies, demonstrates how acupuncture might work in the human body to reduce stress and pain, and potentially depression. We have now found a potential mechanism, and at this point in our research, we need ...
BT.com - Jul 21, 2015
Stimulation with electroacupuncture - a form of the therapy in which a small electric current is passed between a pair of needles - blunted activity in a key hormonal pathway linked to stress, chronic pain and mood, the researchers found. The findings ...
Laboratory Equipment - Jul 21, 2015
In animal models, acupuncture appears to impact the same biologic pathways ramped up by pain and stress, analogous to what drugs do in humans. Georgetown University Medical Center (GUMC) researchers say their animal study, published online in ...
EurekAlert (press release) - Jul 21, 2015
WASHINGTON -- In animal models, acupuncture appears to impact the same biologic pathways ramped up by pain and stress, analogous to what drugs do in humans. Georgetown University Medical Center (GUMC) researchers say their animal study, ...
Original Paper
Effects of Acupuncture, RU-486 on the Hypothalamic-Pituitary-Adrenal Axis in Chronically Stressed Adult Male Rats
Ladan Eshkevari, Susan E. Mulroney, Rupert Egan, and Lixing Lao
Address all correspondence and requests for reprints to: Ladan Eshkevari, PhD, CRNA, LAc,
Georgetown University Medical Center, School of Nursing and Health Studies, 421 St Mary's Hall, 3700 Reservoir Road Northwest, Washington, DC 20007
. E-mail: eshkevl[*a*t*]georgetown.edu.
DOI: http://dx.doi.org/10.1210/EN.2015-1018
Received: January 08, 2015
Accepted: July 07, 2015
First Published Online: July 21, 2015
Effects of Acupuncture,
RU-486 on the Hypothalamic-Pituitary-Adrenal Axis
in Chronically Stressed Adult Male Rats
Ladan Eshkevari, Susan E. Mulroney, Rupert Egan, and Lixing Lao
Address all correspondence and requests for reprints to: Ladan Eshkevari, PhD, CRNA, LAc,
Georgetown University Medical Center, School of Nursing and Health Studies, 421 St Mary's Hall, 3700 Reservoir Road Northwest, Washington, DC 20007
. E-mail: eshkevl[*a*t*]georgetown.edu.
DOI: http://dx.doi.org/10.1210/EN.2015-1018
Received: January 08, 2015
Accepted: July 07, 2015
First Published Online: July 21, 2015
Abstract:
We have recently reported that pretreatment with electroacupuncture (EA) at stomach meridian point 36 (St36) prevents the chronic cold-stress increase in the hypothalamus-pituitary-adrenal axis (HPA), an action that may be under central control. Given that treatment for stress-related symptoms usually begins after onset of the stress responses, the objectives of the present study were to determine the efficacy of EA St36 on HPA hormones when EA St36 is given after stress was initiated, if the results are long lasting, and if blocking the glucocorticoid receptor (GR) using RU-486 had the same effects as EA St36. Adult male rats were placed in 4 groups of animals, 3 of which were exposed to cold and 1 of which was a nontreatment control group.
After exposure to the cold stress, 2 groups were treated with either EA St36 or sham-EA, repeated over 10 days. The increase in ACTH and corticosterone observed in stress-only rats was prevented in EA St36 animals, and the effects remained intact 4 days after withdrawal of EA but continuation of cold stress. When the GR was blocked with RU-486, the efficacy of EA St36 remained unchanged. GR blockade did significantly elevate ACTH, which is not seen with EA St36, suggesting that EA St36 does act centrally.
The elevated HPA hormones in stress-only rats were associated with a significant increase in depressive and anxious behavior; this was not observed in the stressed EA St36 animals. The results indicate that EA specifically at St36 vs sham-EA is effective in treating chronic poststress exposure.
Affiliations
School of Nursing and Health Studies (L.E.),
Department of Pharmacology and Physiology (L.E., S.E.M., R.E.),
Georgetown University Medical Center, Washington, DC 20007; and
School of Chinese Medicine (L.L.), The University of Hong Kong, Pokfulam, Hong Kong
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